Wefound that a history of hypertension; New York Heart Association (NYHA)classification (III and IV vs. I); and abnormal heart rate, high-sensitivetroponin T (hsTnT), N-terminal prohormone of brain natriuretic peptide(NT-proBNP), uric acid, and left ventricular diastolic dysfunction (LVDD) wereall significantly associated with low compliance with GDMT. The gene discussed is NPPB; the disease is Hypertension.