INS and cardiovascular disorder: Several studies have proposed that dietary omega-3 fatty acids protect against cardiovascular disease by lowering risk factors such as blood pressure and heart rate, serum triglycerides, thrombotic tendency, inflammation, and arrhythmias, but also by improving endothelial function, insulin sensitivity, paraoxonase activity, and plaque stability (Ferdinandusse et al., 2001; Masters, 1996; von Schacky and Harris, 2007; Hooper et al., 2006).