Individuals with abdominal obesity often exhibit high levels ofproinflammatory cytokines (tumor necrosis factor-α (TNF-α), interleukin-1α (IL-1α), interleukin-1β (IL-1β), interleukin-6 (IL-6)and interleukin-8 (IL-8)), which can be considered significant prognostic indicators of CVD risk[47, 48]. The gene discussed is IL1A; the disease is Abdominal obesity.