GAS5 and chronic thromboembolic pulmonary hypertension: Wu et al. [92] collected PAECs from CTEPH patientsand rat models and found that SP-induced autophagy interacted with GAS5 in PAECs.In addition, in PAECs, SP treatment reduced the expression level of miRNA-31-5p,which can induce endothelial dysfunction, and vascular remodeling.