Several significantly altered plasma proteinsrelated to inflammatory response (Serum amyloid A protein, C-reactive protein,Protein Adenosine 5’-monophosphate-activated protein kinase (AMPK), Alpha-2-macroglobulin), complement and coagulation cascades(Tetranectin, haptoglobin), and immune response (Neutrophil defensin 3,Fibrinogen beta chain) may contribute to the pathogenesis of COVID-19-relatedAVB. Here, DEFA3 is linked to COVID-19.