Kerchberger et al. [140]identified several single nucleotide polymorphisms associated with new AF in 1936critically ill ICU patients, showing after controlling for clinical factors thatrs3853445 (near PITX2, OR 0.47, 95% CI 0.30–0.73, p = 0.001) andrs12415501 (in NEURL, OR 1.72, 95% CI 1.27–2.59, p = 0.01) wereassociated with new-onset atrial fibrillation. Here, PITX2 is linked to atrial fibrillation.