For the KUMC HF samples, both AFIAS ST2 and ichroma ST2 results were highlycorrelated with Presage ST2 results (r = 0.82 and 0.81, respectively); however,the former showed a positive proportional bias (+21% and +17%, respectively).The mean differences of AFIAS ST2 and ichroma ST2 with Presage ST2 were –4.8ng/mL and –3.7 ng/mL, respectively (Fig. 1). Here, IL1RL1 is linked to hydrops fetalis.