As shown in Fig. 3, we observed a positive association ofRBP4 with the risk of DCM (Fig. 3A: the likelihood ratio test reveals pfor linearity equal to 0.004 with knots at 10th, 50th, and 90th of RBP4 levels,Fig. 3B: p for linearity equal to 0.007 with knots at tertiles of RBP4levels). The gene discussed is RBP4; the disease is familial dilated cardiomyopathy.