SPRY1 and myocardial infarction: Another kindof miRNA, highly expressed miR-21 was observed in cardiac fibroblasts duringacute myocardial infarction as well as transverse aortic constriction (TAC) andenhanced the mitogen-activated protein kinase-extracellular signal-regulatedkinase (MAPK-ERK) signaling pathway by inhibiting false homolog 1 (Spry1) [80].In another study, myocardial infarction decreased the expression of miR-1 andincreased the expression of miR-214.