Figures 7A,B presented the network visualization and density visualization of these top 40 co-cited references. The most frequently cited reference was “Neuroinflammation in Alzheimer’s disease (Heneka et al., 2015)” published in Lancet Neurology, followed by “NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice (Heneka et al., 2013)” in Nature. both authored by Heneka, Michael T. Figure 7C presented the top 20 references with the strongest citation bursts through CiteSpace. This evidence concerns the gene APP and early-onset autosomal dominant Alzheimer disease.