MFRP and Retinal dystrophy: Since then, a Dutch study in 2014 also pointed out that all patients with autosomal recessive inherited MFRP mutations exhibit high hyperopia, but the effect of the mutation on retinal photoreceptor function varies from person to person, and these affected patients usually develop clinical signs of photoreceptor dysfunction or retinal dystrophy later in life (Zenteno et al., 2009).