The heatmap shows that vehicle treatment group had significantly increased expression of CD11b (microglia and MoDMs), B220 (B cells), CD4 (CD4+ T cells), CD8a (CD8+ T cells), CD44 (CD4 Tem and CD8 Tem cells), CD25 (Tregs), CD11c (cDCs), and CD49b (NK cells), indicating an elevated immune response and inflammation following ischemic stroke. The gene discussed is ITGAM; the disease is ischemic stroke.