Furthermore, we observed that plastic EpCAMhigh and EpCAMlow cancer cells did not induce the expression of Tgfb1 and Tgfb2 compared with full epithelial cancer cells (Fig. S1I), ruling out autocrine activation of the TGFβ pathway in epithelial plastic cancer cells to acquire the mesenchymal state. This evidence concerns the gene TGFB2 and cancer.