As expected from the phosphoproteomic analysis, the percentage of pIGF1R+ cancer cells was significantly increased in mixed cSCCs, containing EpCAM+ epithelial plastic cancer cells, whereas this percentage practically disappeared in mesenchymal EpCAMneg cancer cells from mesenchymal cSCCs (Fig. 5D, S4B, and S4C). Here, EPCAM is linked to cancer.