However, “MDS/MPN with ring sideroblasts and thrombocytosis” has been retained as a repository for cases with wild-type SF3B1 and ≥15% ring sideroblasts in both ICC and WHO-HAEM5, as the clinical behavior and biologic features of these infrequent cases is uncertain. This evidence concerns the gene SF3B1 and intrahepatic cholangiocarcinoma.