For instance, m6A-modified circNSUN2 can move to the cytoplasm under the influence of YTHDC1 and may promote liver metastasis in CRC by enhancing HMGA2 mRNA stability through the circNSUN2/IGF2BP2/HMGA2 RNA-protein ternary complex [65]. The gene discussed is YTHDC1; the disease is colorectal carcinoma.