CCL2 and melanoma: [44] The exact patient cohort was also tested for the pre and post treatment levels of cytokines associated with irAEs in lung cancer and melanoma, including IL-17 A, IL‐1β,IL‐6, IL‐8, monocyte chemoattractant protein 1 (MCP‐1), also known as chemokine ligand 2 (CCL2), and TNF-α.