In early pregnancy, TG, ApoA1, ApoB, LDL-c, triglyceride glycaemic index, TG/HDL-c and TC/HDL-c were positively correlated with the risk of GDM, whereas HDL-c was negatively correlated with the risk of GDM, which is consistent with previous reports [22–27]. This evidence concerns the gene APOA1 and gestational diabetes.