Compared with participants without T2DM, those with T2DM are more likely to be male, tended to be older, to have higher levels of BMI, WC, SBP, DBP, TG, Alt, eGFR, Hs-CRP, FBG, PBG2h, HbA1c, WBC and IgA (P for trend < 0.01), but HDL, IgG, IgM and triglyceride-glycemic index (TyG index) were lower (P for trend < 0.001). This evidence concerns the gene CRP and type 2 diabetes mellitus.