These genes were enriched mainly in immune, pyroptosis, and tumor-related biological processes, such as cytokine-mediated signaling pathways, responses to cytokines, responses to tumor necrosis factor, pyroptosis processes, interleukin (IL)-1β production, T cell proliferation, B cell activation, T cell activation, leukocyte homeostasis, and activation of T cells involved in the immune response (Fig. 3A). Here, IL1B is linked to neoplasm.