CRP and Alzheimer disease: In contrast, CRP in both plasma and CSF did not differ among the different diagnosis groups (p = 0.192 and p = 0.832), and only CRP in plasma was higher in females compared to males (p = 0.015, dCohen = 0.2) (Fig. S2), where fewer participants had their CRP measured (n for each group: in blood: n = 50 (CN), 0 (SMC), 0 (EMCI), 337 (LMCI), and 97 (AD); in CSF: n = 74 (CN), 0 (SMC), 0 (EMCI), 133 (LMCI), and 60 (AD)).