For instance, inhibiting PCAT-1 expression in CRC suppresses MYC mRNA expression [58], which may be explained by findings in prostate cancer where PCAT-1 regulates the binding between miR-34A and the 3 ‘untranslated region (UTR) of MYC mRNA, thus reducing its translation [59, 60]. This evidence concerns the gene MYC and Familial prostate cancer.