Next, we evaluated the expression of IMP3 as a proof of principle ribosomal protein relevant to this study, as it has been shown to act as an RNA destabilizing factor resulting in increased eIF4E mediated translation and cell proliferation19 and it is upregulated during EGFR-mediated MAPK activation in triple-negative breast cancer cells20. The gene discussed is IMP3; the disease is triple-negative breast carcinoma.