LRRK2 and Parkinson disease: Parkinson’s disease is a neurodegenerative disease characterized by progressive motor disability and non-motor symptoms.1 To date, seven genes (LRRK2, GBA1, PRKN, SNCA, PINK1, PARK7, VPS35) have been curated by the ClinGen Parkinson’s Disease Gene Curation Expert Panel (PD GCEP) as having a causal relationship with Parkinson’s disease (https://search.clinicalgenome.org/kb/affiliate/10079).