Furthermore, we used GEPIA2 tool to collect the expression data across all TCGA cancers and got the top 200 genes that most correlated with BAX expression, and the top 5 genes are PRPF31 (Pre-MRNA Processing Factor 31, R = 0.52), BBC3 (BCL2 Binding Component 3, R = 0.5), PIH1D1 (PIH1 Domain Containing 1, R = 0.49), LIG1 (DNA Ligase 1, R = 0.49) and PRMT1 (Protein Arginine Methyltransferase 1, R = 0.47). The gene discussed is LIG1; the disease is cancer.