HDAC8 and nonpapillary renal cell carcinoma: According to the chemical structure of the HDAC8 inhibitor (PCI‐34051), we synthesized proteolysis‐targeting chimeras (PROTACs) of HDAC8—HDAC8‐in‐PROTACs—to decrease the protein level of HDAC8 in ccRCC cells (Figure 8A–C).