Additionally, four DETs involved in sperm development, morphogenesis, integrity and fertility were upregulated in viruliferous BLHs, including polycystic kidney disease and receptor for egg jelly-related protein-like isoform X2, probable phospholipid hydroperoxide glutathione peroxidase isoform X1, kelch domain-containing protein 10 and inactive peptidyl-prolyl cis-trans isomerase FKBP6. The gene discussed is KLHDC10; the disease is polycystic kidney disease.