In linear regression models, we identified Raf1‐associated gene pairs in primary tumours relative to cell pools including Raf1‐Pkm2, Raf1‐Top2α, Raf1‐Nqo1, Raf1‐Alox5, Raf1‐Chrnb1 and Raf1‐ Rxra in the model (outlier test, adjusted p < .05) (Figure 3B). This evidence concerns the gene ALOX5 and neoplasm.