This pathway also mediates the binding process of Cell Migration‐inducing and Hyaluronan‐binding Protein (CEMIP) with MEK1, enabling the sustained activation of ERK1/2 and MYC (MYC proto‐oncogene)‐driven transcription in MEK inhibitor‐resistant CRC organoids and cell lines (Figure 2).37 Here, MAP2K7 is linked to colorectal carcinoma.