SJS/TEN has been reported with treatments including anti-programmed-death-1 (PD-1), anti-programmed cell death-ligand 1 (PD-L1), anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), and dual PD-1/CTLA-4 blockade (7, 8). Here, CD274 is linked to Schwartz-Jampel syndrome.