PCNA and ductal breast carcinoma in situ: Ob-MA-T also increased BAX expression by a factor of 3 (RQ=3; p ≤ 0.001) and decreased PCNA expression (RQ=0.3; p ≤ 0.05) while Nw-MA-T did not affect the proliferation and pro-apoptotic activity of MECs of DCIS-like tumoroids but can affect its contractile properties.