TIMP1 and cancer: A significantly decreased TIMP1 expression in cancer cells was observed within Nw-PA-T (RQ=0.322, p ≤ 0.001), Ob-PA-T (RQ=0.099, p ≤ 0.001, p2 = 0.01) (Table 2), Nw-MA-T (RQ=0.579, p ≤ 0.001) and Ob-MA-T (RQ=0.121, p ≤ 0.001, p3 ≤ 0.001) (Table 3), which can contribute to tumor migration and progression.