PTH and Marchiafava-Bignami disease: Unlike the non-progression group, the CKD progression group was also associated with 15.5 % increase in phosphate (3.68 vs 4.25 mg/dL, P value <<0.01) and 94.9 % abnormal increase in PTH (72.3 vs 140.9 pg/dL, P value <<0.01), compatible with CKD-MBD (Fig. 2. and Table 2).