COL4A3 and kidney disorder: Unlike the COL4A3 c.2990G>A variant, the proband’s other variant the, COL4A3 c.4981C>T (p.Arg1661Cys), did not cause any symptoms of kidney disease in her mother, which is consistent with the studies conducted by Sienes et al. (2021) and Braunisch et al. (2018).