ATP6V1B2 and obesity due to melanocortin 4 receptor deficiency: Moreover, genes involved in lysosomal biogenesis and phagocytosis including Atp6v1b2, Atp6v0d2, Lipa, and Lamp2 were also reported to be induced in the ATMs in obesity (Xu, Grijalva et al. 2013, Coats, Schoenfelt et al. 2017).