ALB and neoplasm: We especially focused on an albumin-bound prodrug of monomethylauristatin E (MMAE) and found it blocked tumor growth in mice, delivereda 130-fold greater amount of activated drug to irradiated tumor versusunirradiated tissue, was 7.5-fold more efficient than a non albumin-boundprodrug, and showed no appreciable toxicity compared to free or cathepsin-activatabledrugs.