There are statistically significant differences between the presence and distribution of Salivary Magnesium and Copper, Salivary Leptin and Salivary glucose, BMI and HbA1c (as salivary biomarkers), and Salivary Candida counts, and correlation with the development of BMS, Halitosis, and hyposalivation in patients with type II diabetes mellitus. This evidence concerns the gene LEP and burning mouth syndrome.