GAA and diabetes mellitus: Proper glycaemic control remains the major clinical strategy for managing diabetes and presently the most successful approach for the treatment of diabetes involves the use of hypoglycemic agents (biguanides, sulfonylureas, meglitinide, thiazolidinedione, dipeptidyl peptidase four inhibitors, sodium-glucose cotransporter and alpha-glucosidase inhibitors) together with lifestyle changes.