BDNF and major depressive disorder: Five drugs met these criteria: Topiramate in ATC N03AX (treating epilepsy, targeting GABRA4), Desipramine, Imipramine, and Nortriptyline in ATC N06AA (treating depression and anxiety, targeting BDNF) and Methylphenidate in ATC N06BA (treating ADHD, targeting DRD2).