Of these 1,030 iDMCs, 681 are found within genes and annotate to 695 genes, including the familial PD gene PARK19 (DNAJC6) and PTPRN2, a gene previously implicated in PD and identified in multiple EWAS studies (Fig. 2E,F; Supplementary Files 5,12). Here, PTPRN2 is linked to Parkinson disease.