An international panel of experts on DCM genetics evaluated published evidence on 51 genes relevant to DCM, and they summarized that 12 genes (BAG3, DES, FLNC, LMNA, MYH7, PLN, RBM20, SCN5A, TNNC1, TNNT2, TTN) had definitive or strong evidence, and 7 genes (ACTC1, ACTN2, JPH2, NEXN, TNNI3, TPM1, VCL) had moderate evidence (9). This evidence concerns the gene ACTN2 and familial dilated cardiomyopathy.