Furthermore, Ki-67 showed 40% positivity (Figure 7), and p53 showed positivity in 10-15% of cells. There was scattered positivity for H3k27m (Figure 8), ATRX (alpha-thalassemia/mental retardation, X-linked) was retained in the cell (Figure 9), and epithelial membrane antigen (EMA) was negative. The gene discussed is MUC1; the disease is alpha thalassemia spectrum.