APRI: aspartate aminotransferase to platelet ratio index; AGPR: aspartate aminotransferase to gamma-glutamyl transferase to platelet ratio; AARPRI: aspartate aminotransferase to alanine aminotransferase ratio to platelet ratio index; GPR: gamma-glutamyl transpeptidase to platelet ratio; FIB-4: Fibrosis-4; OR: odds ratio; CI: confidence interval; T2DM: type 2 diabetes mellitus; MetS: metabolic syndrome; *p<0.05 The gene discussed is ALDH18A1; the disease is type 2 diabetes mellitus.