T2DM: type 2 diabetes mellitus; MetS: metabolic syndrome; APRI: AST to platelet ratio index; AARPRI: aspartate aminotransferase to alanine aminotransferase ratio to platelet ratio index; AGPR: aspartate aminotransferase to gamma-glutamyl transferase to platelet ratio; GPR: gamma-glutamyl transpeptidase to platelet ratio; FIB-4: Fibrosis-4; *p<0.05; **p<0.001. This evidence concerns the gene ALDH18A1 and metabolic syndrome.