ACE and congestive heart failure: Patients at increased risk for developing CIN include those above the age of 75 years, female patients, and individuals with previous kidney insufficiency, diabetes mellitus, multiple myeloma, hypertension, congestive heart failure, or those receiving nephrotoxic drugs such as non-steroidal anti-inflammatory drugs, amphotericin B, aminoglycosides, and angiotensin-converting enzyme inhibitors [7].