DES and neoplasm: Immunohistochemically, the neoplasm cells were diffusely positive to desmin (DE-R-11, Ventana), smooth muscle actin (alpha sm-1, Leica, Wetzlar, Germany), H Caldesmon (E89, Cell Marque, Rocklin, CA, US), and MyoD1 (EP212, Cell Marque), and cytoplasmic positivity to β-Catenin (β-catenin-1, Dako, Glostrup, Denmark) while negative to S100 (4C4.9, Ventana, Arizona, US), CD34 (QBEnd /10, Ventana ), factor XIIIa (E980.1, Leica), ALK (5A4, Leica), myogenin (F50; Dako), and EBER (CS.1-4, Dako).