This was followed by a confirmatory serum plasma-free metanephrine and homovanillic acid testing, which also was negative. The patient was referred for genetic counseling, where a hereditary paraganglioma panel was performed using next-generation sequencing testing for several gene mutations, including SDHD, SDHA, RET, VHL, and NF1. The gene discussed is SDHD; the disease is paraganglioma.