PHOSPHO1 and type 2 diabetes mellitus: To test whether epigenetic changes are consistent with previous findings, we analyzed two DNA methylation loci, ABCG1 (cg06500161) and PHOSPHO1 (cg02650017), which are implicated in predicting T2D risk [42]; increased methylation in ABCG1 correlates with a higher T2D risk, while heightened PHOSPHO1 methylation is linked to a reduced risk.