CXCR4 and neoplasm: Tumor-infiltrating monocytes, for instance, express elevated levels of inflammatory cytokines and chemokines such as IL-1β, CXCL2 ,CCL4, and CXCR4, along with cell growth regulators like AREG and EGR1, and markers of tissue residency such as NR4A1, NR4A2, and NLRP3.