IDH3A and neoplasm: T2/fluid-attenuated inversion recovery mismatch signals can identify isocitrate dehydrogenase mutations; magnetic resonance spectroscopy can identify specific metabolites in the region of interest to distinguish tumor necrosis from solid tumor tissue, and can also identify the metabolic products produced by IDH-mutant tumors; diffusion-weighted imaging (DWI) using apparent diffusion coefficient (ADC) measurements from multiple diffusion gradients can predict tumor grading.