NOTCH2NLC and neuronal intranuclear inclusion disease: Boivin et al. determined that the GGC repeat in NOTCH2NLC associated with neuronal intranuclear inclusion disease (NIID) and OPDM3 is embedded within a small upstream open reading frame (uORF) and that, via canonical initiation at an AUG start codon, it encodes a small protein (designated uN2C) comprising five amino acids at the N-terminus, a variable central glycine stretch and 38 amino acids at the C-terminus17.