While preparing this manuscript for submission, a study based exclusively in in vitro assays was published showing that the addition of 25 μM BSO or the use of tools to delete GCLC inhibits the growth of Burkitt lymphoma cell lines under 2D culture conditions [42], seemingly suggesting a comparable susceptibility to glutathione starvation between TICs and differentiated tumor cells. This evidence concerns the gene GCLC and Burkitt lymphoma.