PIK3CA and neoplasm: Additionally, the enrichment of the PI3K pathway was evident in tumor compared to PT samples in the cohort of BCa patients from both the GEO dataset (combined from the two largest BCa datasets with both tumor and normal samples, GSE31189 & GSE13507, n = 223 and 92 respectively, Fig. 1H) as well as TCGA datasets (Fig. 1I).